Modeling the 3D Conformation of Genomes
Guido Tiana (Editor), Luca Giorgetti (Editor)
This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand biophysical mechanisms that control chromosome conformation. The coverage ranges from introductory chapters to modeling aspects related to polymer physics, and data-driven models for genomic domains, the entire human genome, epigenome folding, chromosome structure and dynamics, and predicting 3D genome structure.
類別:
年:
2019
版本:
1
出版商:
CRC Press
語言:
english
頁數:
386
ISBN 10:
1138500798
ISBN 13:
9781138500792
系列:
Series in Computational Biophysics
文件:
PDF, 114.43 MB
IPFS:
,
english, 2019
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